UFC 286: Edwards vs. Usman 3 was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on March 18, 2023, at The O2 Arena in London, England. A UFC Welterweight Championship trilogy bout between current champion Leon Edwards and former champion (also The Ultimate Fighter: American Top Team vs. Blackzilians welterweight winner) Kamaru Usman headlined the event. The pairing first met at UFC on Fox: dos Anjos vs. Cowboy 2 in December 2015, where Usman won by unanimous decision. Their second meeting took place at UFC 278 in August 2022, where Edwards won the title by knockout in the fifth round.

• Ultimate Fighting Championship
• Leon Edwards
• Kamaru Usman
• Justin Gaethje
• Rafael Fiziev
• Gunnar Nelson
• Bryan Barberena
• Jennifer Maia
• Casey O'Neill