FBI agent Neville Flynn boards a flight from Honolulu, Hawaii to Los Angeles, escorting a key witness to testify against a mob boss at an upcoming trial. An on-board assassin releases a crate full of hundreds of deadly venomous snakes in an attempt to eliminate the witness. Flynn and a host of frightened passengers and crew must band together to survive the slithery threat.

• New Line Cinema
• Mutual Film Company
• Samuel L. Jackson
• Julianna Margulies
• Nathan Phillips
• Kenan Thompson
• Rachel Blanchard
• Flex Alexander
• Keith Dallas
• Sunny Mabrey