The movie is set one year after the events of Mafia Family Yanagawa - Part 1, in which 8 Yanagawas faced off against 100 Devil Dragons in an epic bloody battle. Jiro Yanagawa (Takeuchi Riki) continues his feud with the Devil Dragons as he attempts to usurp their western territory.

• Riki Takeuchi
• Kazuyoshi Ozawa
• Yoshiyuki Yamaguchi
• Kyosuke Yabe
• Johnny Ohkura
• Ryo Amamiya
• Hiroki Matsukata
• Shinya Hashimoto