Based on the 2000 book of the same name by Emmanuel Carrère, it is inspired by the real-life story of Jean-Claude Romand. L'Adversaire's protagonist Jean-Marc Faure (Auteuil) pursues an imaginary career as a doctor of medicine in a plot more closely based on Romand's life and Carrère's book than was Laurent Cantet's 2001 film L'Emploi du Temps. The film was nominated for a Palme d'Or at the 2002 Cannes Film Festival.

• Vértigo Films
• Les Films Alain Sarde
• Daniel Auteuil
• Géraldine Pailhas
• François Cluzet
• François Berléand
• Emmanuelle Devos
• Alice Fauvet
• Martin Jobert
• Michel Cassagne