UFC 269: Oliveira vs. Poirier was a mixed martial arts event produced by the Ultimate Fighting Championship that took place on December 11, 2021, at the T-Mobile Arena in Paradise, Nevada, part of the Las Vegas Metropolitan Area, United States. A UFC Lightweight Championship bout between current champion Charles Oliveira and former interim champion Dustin Poirier served as the event headliner.

• Ultimate Fighting Championship
• Charles Oliveira
• Dustin Poirier
• Julianna Peña
• Amanda Nunes
• Geoff Neal
• Santiago Ponzinibbio
• Kai Kara-France
• Cody Garbrandt